Briarenols Q-T: Briaranes from A Cultured Octocoral Briareum stechei (Kukenthal, 1908).

ABSTRACT: Our continuous chemical study of a cultured octocoral Briareum stechei led to the isolation of four new briarane diterpenoids, briarenols Q-T (1-4). The structures of new metabolites 1-4 were established by spectroscopic methods, and compounds 3 and 4 were found to inhibit the generation of inducible nitric oxide synthase (iNOS) from RAW 264.7 stimulated by lipopolysaccharides (LPS).

SUBMITTER: Zhang YL 

PROVIDER: S-EPMC7460508 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature