Severe nausea and vomiting in pregnancy: psychiatric and cognitive problems and brain structure in children.

ABSTRACT:

Background

Two studies have suggested that severe prolonged nausea and vomiting during pregnancy is associated with emotional and behavioral problems in offspring, with smaller sample size and short-term follow-up. Moreover, little information is available on the role of the brain structure in the associations.

Methods

In a US-based cohort, the association was investigated between severe prolonged nausea and vomiting in pregnancy (extending after the second trimester and termed SNVP), psychiatric and cognitive problems, and brain morphology, from the Adolescent Brain Cognitive Development (ABCD) study, from 10,710 children aged 9-11 years. We validated the emotional including psychiatric findings using the Danish National Cohort Study with 2,092,897 participants.

Results<

SUBMITTER: Wang H 

PROVIDER: S-EPMC7460800 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature