The Effects of High-Protein Diets on Kidney Health and Longevity.

ABSTRACT: Although high-protein diets continue to be popular for weight loss and type 2 diabetes, evidence suggests that worsening renal function may occur in individuals with-and perhaps without-impaired kidney function. High dietary protein intake can cause intraglomerular hypertension, which may result in kidney hyperfiltration, glomerular injury, and proteinuria. It is possible that long-term high protein intake may lead to de novo CKD. The quality of dietary protein may also play a role in kidney health. Compared with protein from plant sources, animal protein has been associated with an increased risk of ESKD in several observational studies, including the Singapore Chinese Health Study. Potential mediators of kidney damage from animal protein include dietary acid load, phosphate conten

SUBMITTER: Ko GJ 

PROVIDER: S-EPMC7460905 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature