Association between a history of depression and anti-mullerian hormone among late-reproductive aged women: the Harvard study of moods and cycles.

ABSTRACT:

Background

There is conflicting evidence regarding the association between a history of depression and risk of early menopause. In a cohort of premenopausal women, we investigated the association between depression history and ovarian reserve, as measured by anti-müllerian hormone (AMH).

Methods

The Harvard Study of Moods and Cycles (HSMC) was a prospective cohort study of women living in the Boston, MA metropolitan-area (1995-1999). Women aged 36-45 years at cohort entry (1995) were sampled from seven Boston metropolitan-area communities using census directories. We measured serum AMH in early-follicular phase venous blood specimens from 141 women with a Structured Clinical Interview for DSM-IV (SCID)-confirmed history of depression and 228 without such a history. We calcul

SUBMITTER: Golenbock SW 

PROVIDER: S-EPMC7461252 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature