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Incidence, Progression, and Patterns of Multimorbidity in Community-Dwelling Middle-Aged Men and Women.


ABSTRACT: Background: Determining the incidence, progression, and patterns of multimorbidity are important for the prevention, management, and treatment of concurrence of multiple conditions. This study aimed to analyze major multimorbidity patterns and the association of the onset of a primary condition or combinations of a primary and a secondary condition with the progression to subsequent conditions. Methods: We included 53,867 participants aged 45-64 years from the 45 and Up Study who were free of 10 predefined chronic conditions at baseline (2006-2009). The incidence of multimorbidity (coexistence of ≥2, ≥3, and ≥4 conditions) was identified using the claims database until December 31, 2016. The primary, secondary, tertiary, and quaternary condition for each participant was defin

SUBMITTER: Shang X 

PROVIDER: S-EPMC7461897 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature