Lipid levels and risk of new-onset atrial fibrillation: A systematic review and dose-response meta-analysis.

ABSTRACT: Lipid levels are closely associated with health, but whether lipid levels are associated with atrial fibrillation (AF) remains controversial. We thought that blood lipid levels may influence new-onset AF. Here, we used a meta-analysis to examine the overall association between lipid levels and new-onset AF. PubMed and EMBASE databases were searched up to 20 December 2019. We conducted a systematic review and quantitative meta-analysis of prospective studies to clarify the association between lipid levels and the risk of new-onset AF. Sixteen articles with data on 4 032 638 participants and 42 825 cases of AF were included in this meta-analysis. The summary relative risk (RR) for a 1 mmol/L increment in total cholesterol (TC) was 0.95 (95% CI 0.93-0.96, I² = 74.6%, n = 13). Subgr

SUBMITTER: Yao Y 

PROVIDER: S-EPMC7462197 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature