Predicting the use of antibiotics after initial symptomatic treatment of an uncomplicated urinary tract infection: analyses performed after a randomised controlled trial.

ABSTRACT:

Objective

To predict antibiotic use after initial treatment with ibuprofen using data from a randomised controlled trial comparing ibuprofen to pivmecillinam in the treatment of women with symptoms of an uncomplicated urinary tract infection (UTI).

Setting

16 sites in a primary care setting in Norway, Sweden and Denmark.

Participants

Data from 181 non-pregnant women aged 18-60 presenting with symptoms of uncomplicated UTI, initially treated with ibuprofen.

Methods

Using the least absolute shrinkage and selection operator logistic regression model, we conducted analyses to see if baseline information could help us predict which women could be treated with ibuprofen without risking treatment failure and which women should be recommended antibiotics.

Results

SUBMITTER: Vik I 

PROVIDER: S-EPMC7462246 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature