Accuracy of different diagnostic techniques for Schistosoma haematobium to estimate treatment needs in Zimbabwe: Application of a hierarchical Bayesian egg count model.

ABSTRACT:

Background

Treatment needs for Schistosoma haematobium are commonly evaluated using urine filtration with detection of parasite eggs under a microscope. A common symptom of S. haematobium is hematuria, the passing of blood in urine. Hence, the use of hematuria-based diagnostic techniques as a proxy for the assessment of treatment needs has been considered. This study evaluates data from a national survey in Zimbabwe, where three hematuria-based diagnostic techniques, that is microhematuria, macrohematuria, and an anamnestic questionnaire pertaining to self-reported blood in urine, have been included in addition to urine filtration in 280 schools across 70 districts.

Methodology

We developed an egg count model, which evaluates the infection intensity-dependent sensitivity and

SUBMITTER: Midzi N 

PROVIDER: S-EPMC7462259 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature