Global and regional incidence, mortality and disability-adjusted life-years for Epstein-Barr virus-attributable malignancies, 1990-2017.

ABSTRACT:

Objective

To determine the global and regional burden of Epstein-Barr virus (EBV)-attributed malignancies.

Design

An international comparative study based on the Global Burden of Disease (GBD) Study estimates.

Setting

Global population by age, sex, region, demographic index and time.

Methods and outcome measures

The burden of EBV-attributed Burkitt lymphoma (BL), Hodgkin lymphoma (HL), nasopharyngeal carcinoma (NPC) and gastric carcinoma (GC) was estimated in a two-step process. In the first step, the fraction of each malignancy attributable to EBV was estimated based on published studies; this was then applied to the GBD estimates to determine the global and regional incidence, mortality and disability-adjusted life-years (DALYs) for each malignancy by age, se

SUBMITTER: Khan G 

PROVIDER: S-EPMC7462312 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature