A Randomized Controlled Trial of Behavioral Nudges to Improve Enrollment in Critical Care Trials.

ABSTRACT: Rationale: Low and slow patient enrollment remains a barrier to critical care randomized controlled trials (RCTs). Behavioral economic insights suggest that nudges may address some enrollment challenges.Objectives: To evaluate the efficacy of a novel preconsent survey consisting of nudges on critical care RCT enrollment.Methods: We conducted an RCT in 10 intensive care units (ICUs) among surrogate decision-makers (SDMs). The novel multicomponent behavioral nudge survey was administered immediately before soliciting SDMs' informed consent for their patients' participation in a sham trial of two mechanical ventilation weaning approaches in acute respiratory failure. The primary outcome was the enrollment rate for the sham trial. Secondary outcomes included undue and unju

SUBMITTER: Krutsinger DC 

PROVIDER: S-EPMC7462327 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature