Synthesis of Flower-like Nickel Hydroxide Nanosheets and Application in Electrochemical Determination of Famotidine.

ABSTRACT: An electrochemical sensor was designed and fabricated for electrocatalytic oxidation and determination of famotidine in pharmaceutical forms. The electrochemical oxidation process and its kinetics were investigated using cyclic voltammetry, steady-state polarization measurements, and chronoamperometry techniques, and also the analytical measurements were performed by amperometry. Upon addition of the drug into the solution, cyclic voltammograms of the fabricated sensor exhibited an increased anodic peak current associated with a decrease in the corresponding cathodic current. These results suggested an electrocatalytic EC' oxidation mechanism for famotidine on the oxyhydroxide species immobilized on the electrode surface. Accordingly, a mechanism involving generation of Ni³⁺ act

SUBMITTER: Dehdari Vais R 

PROVIDER: S-EPMC7462516 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature