Heritability of overlapping impulsivity and compulsivity dimensional phenotypes.

ABSTRACT: Impulsivity and compulsivity are traits relevant to a range of mental health problems and have traditionally been conceptualised as distinct constructs. Here, we reconceptualised impulsivity and compulsivity as partially overlapping phenotypes using a bifactor modelling approach and estimated heritability for their shared and unique phenotypic variance within a classical twin design. Adult twin pairs (N = 173) completed self-report questionnaires measuring psychological processes related to impulsivity and compulsivity. We fitted variance components models to three uncorrelated phenotypic dimensions: a general impulsive-compulsive dimension; and two narrower phenotypes related to impulsivity and obsessiveness.There was evidence of moderate heritability for impulsivity (A² = 0.33

SUBMITTER: Tiego J 

PROVIDER: S-EPMC7463011 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature