Ontology highlight
ABSTRACT:
SUBMITTER: Li LC
PROVIDER: S-EPMC7463804 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20200806 16
Simonsinol is a natural sesqui-neolignan firstly isolated from the bark of <i>Illicium simonsii</i>. In this study, the anti-inflammatory activity of simonsinol was investigated with a lipopolysaccharide (LPS)-stimulated murine macrophages RAW264.7 cells model. The results demonstrated that simonsinol could antagonize the effect of LPS on morphological changes of RAW264.7 cells, and decrease the production of nitric oxide (NO), tumor necrosis factor α (TNF-α), and interleukin 6 (IL-6) in LPS-sti ...[more]