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Unravelling the Antibacterial Activity of Terminalia sericea Root Bark through a Metabolomic Approach.


ABSTRACT: Terminalia sericea Burch. ex. DC. (Combretaceae) is a popular remedy for the treatment of infectious diseases. It is widely prescribed by traditional healers and sold at informal markets and may be a good candidate for commercialisation. For this to be realised, a thorough phytochemical and bioactivity profile is required to identify constituents that may be associated with the antibacterial activity and hence the quality of raw materials and consumer products. The aim of this study was to explore the phytochemistry and identify the antibacterial constituents of T. sericea root bark, using a metabolomic approach. The chemical profiles and antibacterial activities of 42 root bark samples collected from three districts in the Limpopo Province, South Africa, were evaluated. Dichloromethane:me

SUBMITTER: Anokwuru CP 

PROVIDER: S-EPMC7464275 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature