Mode and Tempo of Microsatellite Evolution across 300 Million Years of Insect Evolution.

ABSTRACT: Microsatellites are short, repetitive DNA sequences that can rapidly expand and contract due to slippage during DNA replication. Despite their impacts on transcription, genome structure, and disease, relatively little is known about the evolutionary dynamics of these short sequences across long evolutionary periods. To address this gap in our knowledge, we performed comparative analyses of 304 available insect genomes. We investigated the impact of sequence assembly methods and assembly quality on the inference of microsatellite content, and we explored the influence of chromosome type and number on the tempo and mode of microsatellite evolution across one of the most speciose clades on the planet. Diploid chromosome number had no impact on the rate of microsatellite evolution or the amoun

SUBMITTER: Jonika M 

PROVIDER: S-EPMC7464534 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature