Using Genetics in Periodontal Disease to Justify Implant Failure in Down Syndrome Patients.

ABSTRACT: Peri-implant bone loss leading to dental implant failure does not develop in the same way across subjects who apparently present the same condition-specifically, in the case of Down syndrome patients with the same genetic disorder-given that they do not necessarily develop immune-inflammatory disorders to the same extent. This retrospective case-control study was aimed at identifying the possible genes involved in implant failure in Down syndrome patients by matching the periodontal disease variable by means of a retrospective case-control study. This process involved using the functional analysis of gene expression software Transcriptome Analysis Console (TAC, Affymetrix, Thermo Fisher Scientific, Waltham, MA, USA) and a search for the possible candidate genes involved. Focus was placed o

SUBMITTER: Baus-Dominguez M 

PROVIDER: S-EPMC7464703 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature