Diagnostic Performance of Simultaneous [¹⁸F]-FDG PET/MR for Assessing Endoscopically Active Inflammation in Patients with Ulcerative Colitis: A Prospective Study.

ABSTRACT: Background: To investigate the diagnostic performance of simultaneous ¹⁸F-fluoro-deoxyglucose ([¹⁸F]-FDG) PET/MR enterography in assessing and grading endoscopically active inflammation in patients with ulcerative colitis. Methods: 50 patients underwent PET/MR 24 h before ileocolonoscopy. Inflammatory activities of bowel segments were evaluated with both Mayo endoscopic subscore and Nancy histologic index. MR, DWI (Diffusion-weighted imaging) and PET were utilized as qualitative parameters for detecting endoscopically active inflammation. SUVmaxQuot in each segment (maximum of standard uptake value relative to liver) was calculated to quantify inflammation. Results: In the study arm without bowel purgation, combined reading of PET and MR resulted

SUBMITTER: Langhorst J 

PROVIDER: S-EPMC7465255 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature