Lighting Up the Tumor-Fluorescein-Guided Resection of Gangliogliomas.

ABSTRACT: (1) Background: Gangliogliomas comprise a small number of brain tumors. They usually present as World Health Organization (WHO) grade I, and they delineate on gadolinium-enhanced MRI; the surgical goal is wide radical resection, and the course thereafter is usually benign. Fluorescein sodium (FL) tends to accumulate in areas with altered blood-brain barrier (BBB). Thus far, the results provided by prospective and retrospective studies show that the utilization of this fluorophore may be associated with better visualization and improvement of resection for several tumors of the central nervous system. In this study, we retrospectively studied the effect of fluorescein sodium on visualization and resection of gangliogliomas. (2) Methods: Surgical databases in three neurosurgical departments

SUBMITTER: Hohne J 

PROVIDER: S-EPMC7465830 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature