In Silico and In Vitro Analysis of Multifunctionality of Animal Food-Derived Peptides.

ABSTRACT: Currently, the associations between oxidative stress, inflammation, hypertension, and metabolic disturbances and non-communicable diseases are very well known. Since these risk factors show a preventable character, the searching of food peptides acting against them has become a promising strategy for the design and development of new multifunctional foods or nutraceuticals. In the present study, an integrated approach combining an in silico study and in vitro assays was used to confirm the multifunctionality of milk and meat protein-derived peptides that were similar to or shared amino acids with previously described opioid peptides. By the in silico analysis, 15 of the 27 assayed peptides were found to exert two or more activities, with Angiotensin-converting enzyme (ACE) inhibitory, anti

SUBMITTER: Amigo L 

PROVIDER: S-EPMC7466261 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature