Genetic Basis of Natural Variation in Spontaneous Grooming in Drosophila melanogaster.

ABSTRACT: Spontaneous grooming behavior is a component of insect fitness. We quantified spontaneous grooming behavior in 201 sequenced lines of the Drosophila melanogaster Genetic Reference Panel and observed significant genetic variation in spontaneous grooming, with broad-sense heritabilities of 0.25 and 0.24 in females and males, respectively. Although grooming behavior is highly correlated between males and females, we observed significant sex by genotype interactions, indicating that the genetic basis of spontaneous grooming is partially distinct in the two sexes. We performed genome-wide association analyses of grooming behavior, and mapped 107 molecular polymorphisms associated with spontaneous grooming behavior, of which 73 were in or near 70 genes and 34 were over 1 kilobase from the

SUBMITTER: Yanagawa A 

PROVIDER: S-EPMC7467001 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature