Acute kidney injury and kidney replacement therapy in COVID-19: a systematic review and meta-analysis.

ABSTRACT:

Background

Acute kidney injury (AKI) can affect hospitalized patients with coronavirus disease 2019 (COVID-19), with estimates ranging between 0.5% and 40%. We performed a systematic review and meta-analysis of studies reporting incidence, mortality and risk factors for AKI in hospitalized COVID-19 patients.

Methods

We systematically searched 11 electronic databases until 29 May 2020 for studies in English reporting original data on AKI and kidney replacement therapy (KRT) in hospitalized COVID-19 patients. Incidences of AKI and KRT and risk ratios for mortality associated with AKI were pooled using generalized linear mixed and random-effects models. Potential risk factors for AKI were assessed using meta-regression. Incidences were stratified by geographic location and dise

SUBMITTER: Fu EL 

PROVIDER: S-EPMC7467593 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature