Urea-Based Imprinted Polymer Hosts with Switchable Anion Preference.

ABSTRACT: The design of artificial oxyanion receptors with switchable ion preference is a challenging goal in host-guest chemistry. We here report on molecularly imprinted polymers (MIPs) with an external phospho-sulpho switch driven by small molecule modifiers. The polymers were prepared by hydrogen bond-mediated imprinting of the mono- or dianions of phenyl phosphonic acid (PPA), phenyl sulfonic acid (PSA), and benzoic acid (BA) using N-3,5-bis-(trifluoromethyl)-phenyl-Ń-4-vinylphenyl urea (1) as the functional host monomer. The interaction mode between the functional monomer and the monoanions was elucidated by ¹H NMR titrations and ¹H-¹H NMR NOESY supported by molecular dynamic simulation, which confirmed the presence of high-order complexes.

SUBMITTER: Shinde S 

PROVIDER: S-EPMC7467678 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature