Fluoroquinolone Resistance in Clinical Isolates of Klebsiella Pneumonia e.

ABSTRACT: Introduction  Fluoroquinolones are widely used broad-spectrum antibiotics. Recently, increased rate of resistance to this antibiotic has been observed in Klebsiella pneumoniae. The aim of the present study was to determine the presence of quinolone resistance determining regions (QRDR) mutation genes and plasmid-mediated quinolone resistance (PMQR) determinants in clinical isolates of ciprofloxacin-resistant K. pneumoniae. Material and Methods  The study included 110 nonduplicate ciprofloxacin-resistant K. pneumoniae clinical isolates. Antibiotic susceptibility testing by disk diffusion method and minimum inhibitory concentration (MIC) by agar dilution methods for ciprofloxacin was performed according to the recommendations of Clinical Laboratory Standards Institute. The pres

SUBMITTER: Geetha PV 

PROVIDER: S-EPMC7467831 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature