Delayed versus immediate frozen embryo transfer after oocyte retrieval: a systematic review and meta-analysis.

ABSTRACT:

Purpose

This systematic review and meta-analysis aimed to compare pregnancy outcomes between immediate frozen embryo transfer (FET) performed within the first menstrual cycle after oocyte retrieval and delayed FET following subsequent cycles.

Methods

PubMed, EMBASE, and Web of Science were searched for eligible studies through January 2020. The main outcome measures were clinical pregnancy rate (CPR), live birth rate (LBR), and pregnancy loss rate (PLR). The effect size was estimated as risk ratio (RR) with 95% confidence interval (CI) using a random effects model. Inter-study heterogeneity was assessed by the I² statistic.

Results

Twelve retrospective cohort studies involving 18,230 cycles were included. The pooled results revealed no significant differenc

SUBMITTER: Huang J 

PROVIDER: S-EPMC7468025 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature