Detection of copy number variation and selection signatures on the X chromosome in Chinese indigenous sheep with different types of tail.

ABSTRACT:

Objective

Chinese indigenous sheep breeds can be classified into the following three categories by their tail morphology: fat-tailed, fat-rumped and thin-tailed sheep. The typical sheep breeds corresponding to fat-tailed, fat-rumped, and thin-tailed sheep are large-tailed Han, Altay, and Tibetan sheep, respectively. Detection of copy number variation (CNV) and selection signatures provides information on the genetic mechanisms underlying the phenotypic differences of the different sheep types.

Methods

In this study, PennCNV software and F-statistics (FST) were implemented to detect CNV and selection signatures, respectively, on the X chromosome in three Chinese indigenous sheep breeds using ovine high-density 600K single nucleotide polymorphism arrays.

Results

In larg

SUBMITTER: Zhu C 

PROVIDER: S-EPMC7468164 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature