A genome-wide association study of reproduction traits in four pig populations with different genetic backgrounds.

ABSTRACT: OBJECTIVE:Genome-wide association study and two meta-analysis based on GWAS performed to explore the genetic mechanism underlying variation in pig number born alive (NBA) and total number born (TNB). METHODS:Single trait GWAS and two meta-analysis (single-trait meta analysis and multitrait meta analysis) were used in our study for NBA and TNB on 3,121 Yorkshires from 4 populations, including three different American Yorkshire populations (n = 2,247) and one British Yorkshire populations (n = 874). RESULTS:The result of single trait GWAS showed that no significant associated single nucleotide polymorphisms (SNPs) were identified. Using single-trait meta analysis and multi-trait meta analysis within populations, 11 significant loci were identified associated with target traits. Spindlin 1, v

SUBMITTER: Jiang Y 

PROVIDER: S-EPMC7468174 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature