Circadian Variation in Human Milk Composition, a Systematic Review.

ABSTRACT: Breastfeeding is considered the most optimal mode of feeding for neonates and mothers. Human milk changes over the course of lactation in order to perfectly suit the infant's nutritional and immunological needs. Its composition also varies throughout the day. Circadian fluctuations in some bioactive components are suggested to transfer chronobiological information from mother to child to assist the development of the biological clock. This review aims to give a complete overview of studies examining human milk components found to exhibit circadian variation in their concentration. We included studies assessing the concentration of a specific human milk component more than once in 24 h. Study characteristics, including gestational age, lactational stage, sampling strategy, analytical method

SUBMITTER: Italianer MF 

PROVIDER: S-EPMC7468880 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature