XadA2 Adhesin Decreases Biofilm Formation and Transmission of <i>Xylella fastidiosa</i> subsp. <i>pauca</i>.

ABSTRACT: Xylella fastidiosa is a vector-borne bacterium that causes diseases in many plants of economic interest. The bacterium-vector initial interactions involve bacterial membrane-bound adhesins that mediate cell attachment to the foregut of insect vectors. We investigated the role of the afimbrial adhesin XadA2 in the binding and biofilm formation of X. fastidiosa subsp. pauca to vector surfaces in vitro, as well as its potential to disrupt pathogen transmission. We showed that XadA2 has binding affinity for polysaccharides on sharpshooter hindwings, used as a proxy for the interactions between X. fastidiosa and vectors. When in a medium without carbon sources, the bacterium used wing components, likely chitin, as a source of nutrients and formed a biofilm on the win

SUBMITTER: Bossi Esteves M 

PROVIDER: S-EPMC7469142 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature