Systematic analysis reveals cis and trans determinants affecting C-to-U RNA editing in Arabidopsis thaliana.

ABSTRACT:

Background

C-to-U RNA editing is prevalent in the mitochondrial and chloroplast genes in plants. The biological functions of a fraction of C-to-U editing sites are continuously discovered by case studies. However, at genome-wide level, the cis and trans determinants affecting the occurrence or editing levels of these C-to-U events are relatively less studied. What is known is that the PPR (pentatricopeptide repeat) proteins are the main trans-regulatory elements responsible for the C-to-U conversion, but other determinants especially the cis-regulatory elements remain largely uninvestigated.

Results

By analyzing the transcriptome and translatome data in Arabidopsis thaliana roots and shoots, combined with RNA-seq data from hybrids of Arabidopsis thaliana and Arabidopsis lyra

SUBMITTER: Chu D 

PROVIDER: S-EPMC7469343 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature