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The association between analgesic drug use in pregnancy and neurodevelopmental disorders: protocol for an umbrella review.


ABSTRACT:

Background

Maternal prenatal health has been shown to be an important influence on children's developmental outcomes, which has led to an increased emphasis on providing more information to support clinical decisions in pregnancy. Several systematic reviews suggest that analgesic drug use during pregnancy may have neurodisruptive properties. However, no firm conclusions have yet been drawn on the associations between prenatal analgesic drug use and children's long-term development of neurodevelopmental disorders such as autism spectrum disorder (ASD) or attention deficit hyperactivity disorder (ADHD). Therefore, an umbrella review is proposed for the purpose of examining the associations between maternal analgesic drug use during pregnancy and diagnoses of neurodevelopmental disord

SUBMITTER: Kwok J 

PROVIDER: S-EPMC7469356 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature