A Simple Water-Soluble ESIPT Fluorescent Probe for Fluoride Ion with Large Stokes Shift in Living Cells.

ABSTRACT: Developing an effective method for monitoring fluoride ion in biological samples is meaningful because fluoride ion plays a vital role in biological processes. In this contribution, a simple water-soluble ESIPT fluorescent probe 2-((4-((tert-butyldiphenylsilyl)oxy)-1,3-dioxoisoindolin-2-yl)methyl)-1-ethylpyridin-1-ium iodide (SPI) was constructed for monitoring fluoride ion. The probe SPI containing pyridinium salt group exhibited preeminent water solubility. The probe SPI introducing a trimethyldiphenylsilyl ether recognition group displayed excellent selectivity for fluoride ion over other biologically relevant species. Additionally, the probe SPI exhibited a fast response for a fluoride ion, suggesting that it could provide real-time fluoride ion detec

SUBMITTER: Liu X 

PROVIDER: S-EPMC7469414 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature