Illudane Sesquiterpenoids from Edible Mushroom Agrocybe salicacola and Their Bioactivities.

ABSTRACT: To comprehensively understand the chemical constituents of the edible mushroom Agrocybe salicacola and their biological functions, a phytochemical separation of the cultural broth of A. salicacola led to the isolation of four new illudane sesquiterpenoids, agrocybins H-K (1-4), along with 10 known analogues (5-14). Compounds 2-4 were racemates of which 2 and 3 were further separated into single enantiomers as 2a/2b and 3a/3b. All new structures with absolute configurations were elucidated on the basis of an extensive spectroscopic analysis and quantum chemistry calculations. Compound 1 possesses a new carbon skeleton that might be derived from the protoilludane backbone. Compounds 1<

SUBMITTER: Dai Q 

PROVIDER: S-EPMC7469647 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature