Molecular screening of the human parvoviruses B19 and bocavirus 1 in the study of congenital diseases as applied to symptomatic pregnant women and children.

ABSTRACT:

Introduction

B19 virus (B19V) and bocavirus 1 (HBoV1) are human pathogenic parvoviruses that are prevalent worldwide and are responsible for a diverse and not yet fully established spectrum of clinical manifestations.

Objective

To screen B19V and HBoV1 in patients with clinical manifestations associated with acquisition of the infection during gestation.

Methods

A retrospective, observational study was performed that included serum samples from patients without a previous known aetiology. B19V and HBoV1 were determined by end-point PCR. Positive samples were genotyped.

Results

A total of 106 serum samples were analysed, 61 from pregnant women and 45 from neonates and paediatric patients. None were positive for HBoV1, while B19V was detected in 37/106 [34.9 %, 9

SUBMITTER: Salbetti MB 

PROVIDER: S-EPMC7470285 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature