Zwitterionic Molecularly Imprinted Cross-Linked Micelles for Alkaloid Recognition in Water.

ABSTRACT: Molecular imprinting within surface/core doubly cross-linked micelles afforded water-soluble nanoparticle receptors for their template molecules. Extremely strong imprinting effects were consistently observed, with the imprinting factor >100:1 in comparison to nonimprinted nanoparticles prepared without the templates. The ionic nature of the cross-linkable surfactant strongly impacted the imprinting and binding process. Imprinted receptors prepared with a zwitterionic cross-linkable surfactant (4) outperformed a similar cationic one (1) when the template was zwitterionic or cationic and preferred their templates over structural analogues regardless of their ionic characteristics. Electrostatic interactions, however, dominated the receptors made with the cationic surfactant. T

SUBMITTER: Duan L 

PROVIDER: S-EPMC7470345 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature