Score performance of SAPS 2 and SAPS 3 in combination with biomarkers IL-6, PCT or CRP.

ABSTRACT:

Objective

We aimed to evaluate the effects of combining the Simplified-Acute-Physiology-Score (SAPS) 2 or the SAPS 3 with Interleukin-6 (IL-6) or Procalcitonin (PCT) or C-Reactive Protein (CRP) concentrations for predicting in-hospital mortality.

Material and methods

This retrospective study was conducted in an interdisciplinary 22-bed intensive care unit (ICU) at a German university hospital. Within an 18-month period, SAPS 2 and SAPS 3 were calculated for 514 critically ill patients that were admitted to the internal medicine department. To evaluate discrimination performance, the area under the receiver operating characteristic curves (AUROCs) and the 95% confidence intervals (95% CIs) were calculated for each score, exclusively or in combination with IL-6 or PCT or CRP.

SUBMITTER: Jahn M 

PROVIDER: S-EPMC7470390 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature