Prediction of tumor doubling time of lung adenocarcinoma using radiomic margin characteristics.

ABSTRACT:

Background

Because shape or irregularity along the tumor perimeter can result from interactions between the tumor and the surrounding parenchyma, there could be a difference in tumor growth rate according to tumor margin or shape. However, no attempt has been made to evaluate the correlation between margin or shape features and tumor growth.

Methods

We evaluated 52 lung adenocarcinoma (ADC) patients who had at least two computed tomographic (CT) examinations before curative resection. Volume-based doubling times (DTs) were calculated based on CT scans, and patients were divided into two groups according to the growth pattern (GP) of their ADCs (gradually growing tumors [GP I] vs. growing tumors with a temporary decrease in DT [GP II]). CT radiomic features reflecting margin

SUBMITTER: Yoon HJ 

PROVIDER: S-EPMC7471031 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature