Combined neat model for the prognosis of postoperative stage III-N2 non-small cell lung cancer.

ABSTRACT:

Background

Lung cancer serum tumor markers including carcinoembryonic antigen (CEA), cytokeratin 19 fragment (CYFRA21-1), and carbohydrate antigen 125(CA125) as prognostic predictors is controversial. Therefore, this study aimed to evaluate the association between these markers and the survival of patients with postoperative stage III-N2 non-small cell lung cancer (NSCLC).

Methods

We enrolled 1011 patients with pathologically confirmed stage III-N2 NSCLC who underwent resection and whose pretreatment serum tumor marker levels were available. Patients were categorized according to their serum levels into low-, medium-, and high-risk groups. Overall survival (OS), progression-free survival (PFS), local regional relapse-free survival (LRFS), and distant metastasis-free survival

SUBMITTER: Zhai Y 

PROVIDER: S-EPMC7471036 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature