Bipartite Functional Fractionation within the Default Network Supports Disparate Forms of Internally Oriented Cognition.

ABSTRACT: Our understanding about the functionality of the brain's default network (DN) has significantly evolved over the past decade. Whereas traditional views define this network based on its suspension/disengagement during task-oriented behavior, contemporary accounts have characterized various situations wherein the DN actively contributes to task performance. However, it is unclear how different task-contexts drive componential regions of the DN to coalesce into a unitary network and fractionate into different subnetworks. Here we report a compendium of evidence that provides answers to these questions. Across multiple analyses, we found a striking dyadic structure within the DN in terms of the profiles of task-triggered fMRI response and effective connectivity, significantly extending beyond

SUBMITTER: Chiou R 

PROVIDER: S-EPMC7472201 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature