Skeleton optimization of neuronal morphology based on three-dimensional shape restrictions.

ABSTRACT:

Background

Neurons are the basic structural unit of the brain, and their morphology is a key determinant of their classification. The morphology of a neuronal circuit is a fundamental component in neuron modeling. Recently, single-neuron morphologies of the whole brain have been used in many studies. The correctness and completeness of semimanually traced neuronal morphology are credible. However, there are some inaccuracies in semimanual tracing results. The distance between consecutive nodes marked by humans is very long, spanning multiple voxels. On the other hand, the nodes are marked around the centerline of the neuronal fiber, not on the centerline. Although these inaccuracies do not seriously affect the projection patterns that these studies focus on, they reduce the accurac

SUBMITTER: Jiang S 

PROVIDER: S-EPMC7472589 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature