Inter-scanner reproducibility of brain volumetry: influence of automated brain segmentation software.

ABSTRACT:

Background

The inter-scanner reproducibility of brain volumetry is important in multi-site neuroimaging studies, where the reliability of automated brain segmentation (ABS) tools plays an important role. This study aimed to evaluate the influence of ABS tools on the consistency and reproducibility of the quantified brain volumetry from different scanners.

Methods

We included fifteen healthy volunteers who were scanned with 3D isotropic brain T1-weighted sequence on three different 3.0 Tesla MRI scanners (GE, Siemens and Philips). For each individual, the time span between image acquisitions on different scanners was limited to 1 h. All the T1-weighted images were processed with FreeSurfer v6.0, FSL v5.0 and AccuBrain^® with default settings to obtain volumetry of b

SUBMITTER: Liu S 

PROVIDER: S-EPMC7472704 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature