Pickering emulsions stabilized by colloidal gel particles complexed or conjugated with biopolymers to enhance bioaccessibility and cellular uptake of curcumin.

ABSTRACT: The aim of this study was to investigate the fate of curcumin (CUR)-loaded Pickering emulsions with complex interfaces during in vitro gastrointestinal transit and test the efficacy of such emulsions on improving the bioaccessibility and cellular uptake of CUR. CUR-loaded Pickering emulsions tested were whey protein nanogel particle-stabilized Pickering emulsions (CUR-E_WPN) and emulsions displaying complex interfaces included 1) layer-by-layer dextran sulphate-coated nanogel-stabilized Pickering emulsions (CUR-DxS+E_WPN) and 2) protein+dextran-conjugated microgel-stabilized Pickering emulsions (CUR-E_WPDxM). The hypothesis was that the presence of complex interfacial material at the droplet surface would provide better protection to the droplets agains

SUBMITTER: Araiza-Calahorra A 

PROVIDER: S-EPMC7473359 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature