Ultrasound Characterization of Disordered Antral Follicle Development in Women with Polycystic Ovary Syndrome.

ABSTRACT: The mechanism of oligo-anovulation in polycystic ovary syndrome (PCOS) is unknown. To evaluate follicular and endocrine characteristics of anovulatory and sporadic ovulatory cycles in women with PCOS. Prospective, longitudinal study. Academic clinical research unit. 26 reproductive-aged women (18-38 years) with PCOS, observed during natural anovulatory (PCOS-Anov; n = 12) and sporadic ovulatory cycles (PCOS-Ov; n = 14), and 12 controls. Transvaginal ultrasonography and venipuncture were performed every other day for 4 to 6 weeks in women with PCOS or at 1 interovulatory interval in control subjects. Follicle number and diameter (ie, ≥2 mm) were quantified at each visit. Individual growth profiles were assessed for all follicles that grew to ≥7 mm. Blood samples were assayed for follicle-st

SUBMITTER: Jarrett BY 

PROVIDER: S-EPMC7473602 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature