The impact of persistent colonization by Vibrio fischeri on the metabolome of the host squid Euprymna scolopes.

ABSTRACT: Associations between animals and microbes affect not only the immediate tissues where they occur, but also the entire host. Metabolomics, the study of small biomolecules generated during metabolic processes, provides a window into how mutualistic interactions shape host biochemistry. The Hawaiian bobtail squid, Euprymna scolopes, is amenable to metabolomic studies of symbiosis because the host can be reared with or without its species-specific symbiont, Vibrio fischeri In addition, unlike many invertebrates, the host squid has a closed circulatory system. This feature allows a direct sampling of the refined collection of metabolites circulating through the body, a focused approach that has been highly successful with mammals. Here, we show that rearing E. scolopes with

SUBMITTER: Koch EJ 

PROVIDER: S-EPMC7473655 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature