Exploring functional brain activity in neonates: A resting-state fMRI study.

ABSTRACT: The human brain is born with a certain maturity, but quantitatively measuring the maturation and development of functional brain activity in neonates remains a topic of vigorous scientific research, especially the dynamic characteristics. To address this, T1w, T2w, and resting-state functional magnetic resonance imaging (rs-fMRI) data from 40 full-term healthy neonates and 38 adults were adopted in this study. Group differences of local brain activity and functional connectivity between neonates and adults from both static and dynamic perspectives were explored. We found that the neonatal brain is largely immature in general. Sensorimotor areas were the most active, well-connected, and temporally dynamic. Compared with adults, visual and primary auditory areas in neonates showed higher or

SUBMITTER: Huang Z 

PROVIDER: S-EPMC7474406 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature