Contributions of elastic fibers, collagen, and extracellular matrix to the multiaxial mechanics of ligament.

ABSTRACT: Elastin is a biopolymer known to provide resilience to extensible biologic tissues through elastic recoil of its highly crosslinked molecular network. Recent studies have demonstrated that elastic fibers in ligament provide significant resistance to tensile and especially shear stress. We hypothesized that the biomechanics of elastic fibers in ligament could be described as transversely isotropic with both fiber and matrix components in a multi-material mixture. Similarly, we hypothesized that material coefficients derived using the experimental tensile response could be used to predict the experimental shear response. Experimental data for uniaxial and transverse tensile testing of control tissues, and those enzymatically digested to disrupt elastin, were used as inputs to a material coef

SUBMITTER: Henninger HB 

PROVIDER: S-EPMC7474469 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature