Outpatient Worsening Heart Failure as a Target for Therapy: A Review.

ABSTRACT:

Importance

Hospitalizations for worsening heart failure (WHF) represent an enormous public health and financial burden, with physicians, health systems, and payers placing increasing emphasis on hospitalization prevention. In addition, maximizing time out of the hospital is an important patient-centered outcome. In this review, we discuss the concept of outpatient WHF, highlight the rationale and data for the outpatient treatment of WHF as an alternative to hospitalization, and examine opportunities and strategies for developing outpatient "interceptive" therapies for treatment of worsening symptoms and prevention of hospitalization.

Observations

Worsening heart failure has traditionally been synonymous with an episode of in-hospital care for worsening symptoms. While WHF of

SUBMITTER: Greene SJ 

PROVIDER: S-EPMC7474527 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature