Pervasive Phenotypic Impact of a Large Nonrecombining Introgressed Region in Yeast.

ABSTRACT: To explore the origin of the diversity observed in natural populations, many studies have investigated the relationship between genotype and phenotype. In yeast species, especially in Saccharomyces cerevisiae, these studies are mainly conducted using recombinant offspring derived from two genetically diverse isolates, allowing to define the phenotypic effect of genetic variants. However, large genomic variants such as interspecies introgressions are usually overlooked even if they are known to modify the genotype-phenotype relationship. To have a better insight into the overall phenotypic impact of introgressions, we took advantage of the presence of a 1-Mb introgressed region, which lacks recombination and contains the mating-type determinant in the Lachancea kluyveri budding yeast. By pe

SUBMITTER: Brion C 

PROVIDER: S-EPMC7475044 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature