Viral etiology and atopic characteristics in high-risk asthmatic children hospitalized for lower respiratory tract infection.

ABSTRACT:

Background

Viral etiology and atopic characteristics, e.g., allergens and fractional exhaled nitric oxide (FeNO), play essential roles in asthma development. This study aimed to investigate associations among them in children at high risk of developing asthma to guide reliable diagnosis and treatment of wheezing.

Methods

From April 2016 to August 2017, 135 children aged <3 years identified as being at high risk of asthma and hospitalized for lower respiratory tract infection (LRTI) with wheezing were recruited as research subjects (observation group). Real-time fluorescent polymerase chain reaction (PCR) was used to explore their etiology. Samples were also evaluated with Phadiatop (Pharmacia Diagnostics AB, Uppsala, Sweden). Additionally, 200 non-asthmatic, non-allergic, he

SUBMITTER: Wang T 

PROVIDER: S-EPMC7475309 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature