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The efficacy and safety of a ketogenic diet for children with refractory epilepsy in China: a retrospective single-center cohort study.


ABSTRACT:

Background

The ketogenic diet (KD) has been implemented in many different counties. However, in China, study concerning the efficacy of the KD is still at an early-stage of evaluation. Furthermore, the KD is thought to be incompatible with Chinese children because of its lack of palatability, especially for the Asian population. In addition, its substantial antiepileptic effect remains to be confirmed.

Methods

To evaluate the efficacy and safety of the KD treatment of refractory childhood epilepsy in China, we prospectively enrolled 147 children with refractory epilepsy for KD treatment in Guangdong 999 Brain Hospital and followed up the children for 6 months. Outcome was measured by seizure frequencies before and after the KD diet and adverse effects. We also evaluated infl

SUBMITTER: Li H 

PROVIDER: S-EPMC7475313 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature