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Which is the optimal management for locally advanced gastric cancer patients with TRG 0 and 1 after R0 resection?


ABSTRACT:

Background

Neoadjuvant chemotherapy (NAC) followed by surgery currently offers promise as a strategy for patients with locally advanced gastric cancer (GC). However, there is limited evidence to guide treatment for TRG 0 and 1 patients with locally advanced GC after R0 resection. This study set out to explore the optimal management for TRG 0 and 1 patients with locally advanced GC after R0 resection.

Methods

The retrospective data of 154 TRG 0 and 1 patients with locally advanced GC following R0 resection who were treated between January 2012 and December 2018 were collected and analyzed. The Kaplan-Meier method was used to estimate the survival rate. Multivariate analysis was performed using the Cox proportional hazards model.

Results

The median follow-up was 34.1 (r

SUBMITTER: Ma F 

PROVIDER: S-EPMC7475443 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature